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Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. Fortunately, it is also treatable. Depression causes feelings of sadness and/or a loss of interest in activities once enjoyed. It can lead to a variety of emotional and physical problems and can decrease a person’s ability to function at work and at home.

Depression symptoms can vary from mild to severe and can include:

• Feeling sad or having a depressed mood

• Loss of interest or pleasure in activities once enjoyed

• Changes in appetite — weight loss or gain unrelated to dieting

• Trouble sleeping or sleeping too much

• Loss of energy or increased fatigue

• Increase in purposeless physical activity (e.g., hand-wringing or pacing) or slowed movements and speech (actions observable by others)

• Feeling worthless or guilty

• Difficulty thinking, concentrating or making decisions

Experiencing occasional anxiety is a normal part of life. However, people with anxiety disorders frequently have intense, excessive and persistent worry and fear about everyday situations.

These feelings of anxiety and panic interfere with daily activities, are difficult to control, are out of proportion to the actual danger and can last a long time. You may avoid places or situations to prevent these feelings. Symptoms may start during childhood or the teen years and continue into adulthood.

Examples of anxiety disorders include generalized anxiety disorder, social anxiety disorder (social phobia), specific phobias and separation anxiety disorder. You can have more than one anxiety disorder. Sometimes anxiety results from a medical condition that needs treatment.

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Common anxiety signs and symptoms include:

• Feeling nervous, restless or tense

• Having a sense of impending danger, panic or doom

• Having an increased heart rate

• Breathing rapidly (hyperventilation)

• Sweating

• Trembling

• Feeling weak or tired

• Trouble concentrating or thinking about anything other than the present worry

• Having trouble sleeping

• Experiencing gastrointestinal (GI) problems

• Having difficulty controlling worry

• Having the urge to avoid things that trigger anxiety

There are three main symptoms that can occur with bipolar disorder: mania, hypomania, and depression.

While experiencing mania, a person with bipolar disorder may feel an emotional high. They can feel excited, impulsive, euphoric, and full of energy. During manic episodes, they may also engage in behavior such as:

• spending spree

• drug use

• deep sadness

• hopelessness

• loss of energy

• lack of interest in activities they once enjoyed

• periods of too little or too much sleep